News

Paradigm4 Launches Precision Cell Atlas™

Paradigm4 has launched the Precision Cell AtlasTM as an integral component of its REVEALTM: SingleCell app. The Precision Cell Atlas enables scientists to create a custom cell atlas by selectively combining an unlimited number of samples from multiple datasets for specific research objectives and explicitly saving them for collaboration, reuse, and regulatory filings.

REVEAL: SingleCell, together with the Precision Cell Atlas capability, includes industry standard statistical tools to assess the sample-to-sample variation in gene vectors while retaining the provenance from the original project metadata for each sample. Metadata is tracked in the immutable log files recorded with REVEAL: SingleCell.

With its initial launch in 2020, REVEAL: SingleCell was developed to offer biopharmaceutical computational biologists the ability to break through the data wrangling and programming challenges associated with the analysis of large-scale, single-cell datasets. The app enables users to navigate multimodal disease biology, scale to handle more samples from patients with more cells, more features, and diverse data types. Users can readily assess key biological hypotheses for target evaluation, disease progression, and precision medicine applications.

Paradigm4’s REVEAL suite of use case-specific applications were built to transform scalable translational understanding from whole body to organelle. Other apps developed by Paradigm4 include REVEALTM: Proteomics and REVEALTM: Biobank. The apps are powered by Paradigm4’s unique technology stack, designed for scalable and interactive exploration, analytics, and machine learning on heterogeneous and highly dimensional scientific data sets.

Zachary Pitluk, Ph.D., VP of Life Sciences and Healthcare at Paradigm4, commented: “Since its launch, REVEAL: SingleCell has been embraced by the single cell analysis community, with as many as 80 million cells in play in some installations. Current customer installations are supporting thousands of queries per day with the present implementation. Importantly, the addition of the Precision Cell Atlas functionality should increase the supportable queries and drive projects forward at a much faster rate than is currently available.”

For more information about Paradigm4, visit https://paradigm4.com/.

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54gene Enlists Paradigm4’s Science-Ready Data Solution for its African Health Information Ecosystem

12 JANUARY 2021: Paradigm4, specialist in scientific data management and scalable computation, has signed an agreement with 54gene, a health technology company deriving insights from the world’s most diverse populations to solve some of healthcare’s biggest challenges. The agreement will allow 54gene to use Paradigm4’s REVEALTM Biobank app to explore,

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BioPharma Trend: A new way to work with data in life sciences

Interview with Marilyn Matz, CEO and Co-founder at Paradigm4, and 2020 NACD Directorship 100™ honoree, and her colleague Dr. Zachary Pitluk, VP of Life Sciences and Health Care at Paradigm4. Founded by renowned database researcher, Turing Award laureate MIT Professor Michael Stonebraker, Paradigm4 is not just any data analytics company

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Bio-IT World || Lessons From the Recent HCA 2022 General Meeting: Applying Single-Cell Data to Clinical Decision Making

The recent Human Cell Atlas (HCA) 2022 General Meeting, hosted in Vienna, Austria, provided a great opportunity for me to catch up on progress towards the HCA’s goal of mapping every cell type in the human body. I also got the chance to hear presentations that either highlighted new insights